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Nature of Adverse Events The most commonly reported fatal complications include: Acute pancreatitis : Sudden inflammation of the pancreas, often requiring hospitalization and linked to severe abdominal pain, nausea, and fever Organ failure : In some cases, GLP-1RA drugs have been suspected of contributing to multi-organ dysfunction Cardiovascular events : Though rare, some deaths have involved cardiac arrest or stroke following GLP-1RA use Complications from off-label or unsupervised use : Several cases involved individuals obtaining GLP-1RA drugs from unregulated online sources or using counterfeit pens Its important to note that these reports do not confirm causality

Hota KB, Hota SK, Chaurasia OP, Singh SB

C s 2: Tam Hip, Thanh Tr, H Ni

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it protects tissue from further damage by modulating the inflammatory cascade systemically