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This scenario contrasts with the apparent lack of effect of high doses of GLP-1 (9-36amide) on glucoregulation in ob/ob mice or on cognitive function in high-fat fed mice [202,203]

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10.1038/sj.bmt.1705761 95

P., Kesteven, P

Using transgenic mice expressing yellow fluorescent protein (YFP) under the control of the glucagon promoter (PPG-YFP mice) 18 , we identified a population of PPG neurons in the granular cell layer (GCL) of the OB (Fig