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This advanced formulation is particularly beneficial for individuals at increased risk of deficiency, including the elderly, vegetarians, vegans, and those with GI conditions that hinder B12 absorption, such as pernicious anemia, celiac disease, Crohns disease, and irritable bowel syndrome (IBS), among others

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Concurrently, PUFA accumulation drives ferroptosis, positioning SCD1 as a critical regulator of this cell death pathway [80, 81]

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Furthermore, ROS are involved in DNA damage, including mtDNA damage, and induces mitochondrial apoptosis