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Role of advanced glycation end products in diabetic neuropathy

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Patients should avoid making rapid dietary changes or severely restricting food intake beyond what naturally occurs from reduced appetite, as extreme caloric restriction can worsen gastrointestinal symptoms and compromise nutritional status

moderate quality evidence) (Jamilian et al., 2019a)

Wegovy (semaglutide), which was approved in 2021 (it was previously available for diabetes as Ozempic and in an oral form for diabetes as Rybelsus)