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These likely include genetic variation in the rest of the genome, encompassing the modifying impact of additional rare variants [91] and the aggregate effects of common variants [92], environmental effects, and variation resulting from stochastic events during brain development, to whose influence individuals with high-impact variants may be particularly susceptible [19, 93]

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With over 40% of patients who take oral dopamine agonists experience impulse control disorders, CBT could be a new method to treat serious associated adverse effects of the necessary medications taken [44]