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But, the ACh/7nAChR axis exerts anti-inflammatory effects, suppressing NF-B in macrophages (Wang et al., 2003) and ILC2 with the subsequent reduction of a similar Th2 profile attenuating bronchial inflammation (Galle-Treger et al., 2016)
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The name originated in online fitness and recovery communities as a reference to the Marvel character's regenerative abilities, and has since become the standard industry term for this combination