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It doesn't mean that there's a causation, but we see a correlation

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their dysfunction leads to energy deficits that manifest as fatigue and slowed healing

10.1155/2022/6520789 84 LiY.JinC.ShenM.WangZ.TanS.ChenA.et al (2020b)

95% CI [1.181.49]) and mortality (aOR 1.36