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Persistent bile acid accumulation activates Kupffer cells through TLR4, especially in the presence of LPS, and bile acid crystals activate the NLRP3 inflammasome, producing TNF-, IL-1, and IL-6 [44]

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Di aku, tanda-tanda kulit lebih sehat baru mulai kelihatan setelah sekitar 34 minggu pemakaian rutin