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Long-term corticosteroid use in SLE is significantly associated with permanent organ damage, including osteoporotic fractures, diabetes, cataracts, avascular necrosis, and symptomatic coronary artery disease (108)

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If a pregnancy occurs during this time, it creates an environment in which mother and fetus compete for nutrients, as both parties are undergoing major developmental changes throughout gestation

High blood pressure can harm the kidneys over time

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However, not every patient with these conditions is a suitable candidate