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A potent endogenous antioxidant, glutathione is essential for the livers phase I and phase II detoxification.* However, negative lifestyle issues and adverse conditions that affect liver health can result in a decreased amount of glutathione in the liver
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doi: 10.1016/j.cell.2024.01.030 19 ConradMPrattDA
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This Ca 2+ influx, along with elevated ATP, results in exocytosis of the plasma membrane docked immediate release pool (IRP) of insulin granules, a sub-pool of the readily releasable pool (RRP) which contains ~15% of available insulin granules ( st phase stimulus-secretion coupling, since it is the products of glucose catabolism that ultimately drive insulin exocytosis
