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Loss of NF1 gene function, mutations in TP53 or CDKN2A/B, and expression of SOX10, H3K27me3 loss, or PRC2 complex mutations may support the diagnosis of MPNST (Reuss et al., 2020)

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long-acting analogs such as cagrilintide are widely investigated in obesity and metabolic research, frequently alongside GLP-1 receptor agonists

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