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Cohort 2: In Cohort 2, we sought to determine if nicotine causally affects the brain circuits we identified in Cohort 1 as associated with nicotine dependence

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In addition to the devices, dozens of high-nicotine e-liquids have arrived on the market with names such as "frozen mystery pop," "rainbow drops" and "Tokyo chocolate banana," which critics say are designed to attract young customers

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