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Addictive behaviours have been linked to glutamate dysregulation, and the benefits of NAC are thought to be mediated by its effect on glutamate homeostasis

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In this study, riboflavin administration reversed the decline in GR and GPx activities and GSH content of lung induced by LPS

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However, and interestingly, data also suggested that while GSTP1-1 engages TRAF2 in its dimeric form, only one monomer is involved in binding and therefore the other may still be catalitically competent 30