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The Atherosclerosis Risk in Communities (ARIC) study

This distinction matters because the hormone and its receptor activator are different pharmacological entities, each with unique dosing, mechanism, and clinical profile

Lu Y, Sun J, Yang M, Xing Y, Zhu W, Zhu J, et al

Dosage & Administration

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Morphine, for instance, produced greater opioid tolerance when compared with agonists like DAMGO, sufentanil, or etorphine, when equivalent induction doses and continuous infusions were used to control for pharmacokinetic differences (Stevens and Yaksh 1989