SLC25A45 shares a structural homology to SLC25A48 that transports choline as a substrate ( 3032 ), which also bears a N -trimethyl moiety (50% and 68% of sequence identity and conservation, respectively)
This allows for deeper study of pathway-specific activity without the confounding effects of poly-compound blends
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Ohkawa, Takumi [Biological and Pharmaceutical Bulletin, 2004, vol