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In male Wistar rats experiencing transient ischemic stroke, UA suppresses the upregulation of cerebrocortical Vegfa expression in the acute phase of stroke and reduces the MMP-9/TIMP-1 ratio in the brain cortex, indicating that UA treatment may aid in the downregulation of the VEGF-A/MMP-9 pathway to improve BBB integrity [54]

doi: 10.1016/j.celrep.2020.107987 32 QuJQinLGuoJZhuLLuoYLiCet al

In documents preparing for the hearing, FDA scientists noted that the peptides under discussion aren't well-understood or sufficiently studied, per NYT

Glucose-6-phosphate dehydrogenase deficiency and neonatal jaundice in Nigeria

Pharmacology & Therapeutics

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