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13 / 13 Talk to your doctor about B12 supplements, both during pregnancy and breastfeeding

If digestion feels steadier, some individuals may adhere more consistently to nutrition targets

However, some people experience mild stomach discomfort with empty stomach dosing, in which case taking with a small amount of food is acceptable

doi: 10.1007/s12975-011-0125-x 126

The selected per-injection dose remains fixed at 1.64.8 mg across all three phases, while frequency changes from daily to 5 per week to 23 per week for maintenance, followed by 48 weeks off

The increased heart rate effect may be poorly tolerated in patients with limited cardiac reserve