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288,289 In one study, 44% of untreated patients but 38%, 28% and 9% of patients treated with CRS, CBT-I, and CBT-I + CRS, respectively, experienced clinically significant worsening of depressive symptoms during a 1-year follow-up period

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Chronic liver injury induces conversion of biliary epithelial cells into hepatocytes

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18 NAC has also been shown to have direct antibacterial effects, adding to its biofilm-disrupting potential