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15,453,454 Current therapeutic approaches for hyperuricemia focus on mitigating associated complications and reducing serum UA levels with non-pharmacological interventions include dietary modifications and some environment factors

They can load and selectively release a controlled dosage of drug molecules in a specific targeted site, improving the efficiency of therapeutic agents ( in vivo pulsatile release of several types of physiological chemicals, such as hormones, like estrogen and insulin (Figure 1)

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