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Its mechanism simultaneously targets: GLP-1 receptors: improving insulin secretion, lowering blood glucose, and suppressing appetite GCG receptors: increasing energy expenditure, promoting fat oxidation, and improving hepatic lipid metabolism Approved indications in China include: Long-term weight management in overweight or obese adults Blood glucose control in type 2 diabetes Clinical trial findings related to Mazdutide have been published in leading journals including Nature, The New England Journal of Medicine, and JAMA

doi:10.1161/STROKEAHA.125.053075 83

That contrast is one of the sharpest in the table and supports the post's argument that the two classes are not interchangeable

Frequently Asked Questions Does semaglutide cause fewer side effects than tirzepatide