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2025;4:100569 DOI: Received: February 19, 2025 Accepted: March 25, 2025 Published: April 07, 2025 Academic Editor: Maria L

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We hope this review provides a starting point on which future publications can build and deepen our understanding of these important topics

Based on these researches, clinical trials targeting HO-1 should be carried out to evaluate its application in the treatment of DN, so as to provide evidence for clinical application

For gastrointestinal applications, digestive comfort may improve within the first 1 to 2 weeks, progressing to sustained improvements in food tolerances by weeks 5 to 6