While long-term glycemic control unequivocally reduces the risk of developing and progressing diabetic retinopathy (as demonstrated in the DCCT and UKPDS trials), rapid reduction in blood glucose levels can paradoxically cause temporary worsening of existing retinopathya phenomenon termed "early worsening" or "acute progression." This phenomenon was first documented in the Diabetes Control and Complications Trial (DCCT) and has been observed with intensive insulin therapy and other glucose-lowering interventions
This might involve reducing the dosage or switching to medications with a lower risk of hypoglycemia
They are not indicated for type 1 diabetes or diabetic ketoacidosis
Preventive Care: Beyond managing respiratory symptoms, nebulized glutathione has the potential to serve as a preventive intervention, reducing the risk of exacerbations and complications in high-risk populations
Lancet 1971;1:519-22 Rumack BH,Mathew H,Acetamenophen poisoning and toxicity.peddiatrics 1975;55:871-6 Daly FF, Fountain JS,Murray L,Graudins A,Buckley NA,Guidelines for the management of paracetamol in Australia and New Zealand- explanation and elaboration.A consessus statement from clinical toxicologists consulting to the Australasian poisons information centres
Gastrointestinal side effects and bleeding risk: According to the Wegovy SmPC, common adverse effects include nausea (very common), diarrhoea (very common), vomiting (very common), and constipation (very common)
