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Wu B, Chen Q, Cao R, Zhu L, Zhu H (2024) Comparative effectiveness of combined biologic agents versus standard therapies in the treatment of plaque psoriasis: a retrospective analysis

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Paradoxical Decreases in Heart Rate at Low Sub-Therapeutic Doses of Atropine (1) a central vagotonic mechanism , whereby low-dose atropine blocks inhibitory M1 muscarinic receptors in the central nervous system or parasympathetic ganglia, disinhibiting vagal outflow and increasing parasympathetic tone to the sinoatrial node (Kotona et al, 1977

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Abbreviations BBD: Box-Behnken design BSA: Bovine serum albumin DTNB: (5,5-dithiobis-(2-nitrobenzoic acid) GPx: Glutathione peroxidase GSH: Reduced glutathione GSSG: Oxidized glutathione LOD: Limits of detection LOQ: Limits of quantitation RSM: Response surface modeling TBuOOH: Tert-Butyl hydroperoxide TNB: Nitro-2-thiobenzoate anion WSAVA: World Small Animal Veterinary Associations References Ademi M (2023) The role of ionized water and its impact on the activity of glutathione peroxidase on rats blood serum during hyperthermic stress

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