Macrophage Cell Death and Efferocytosis Influence Plaque Stability The necrotic core results from a combination of accelerated macrophage death and impaired efferocytosis (receptor-mediated phagocytosis of apoptotic cells) (Figure 5) (171,172)
Analysis of effectiveness of treatment (main outcome) at the three monitoring points Intention-to-treat and per-protocol analyses will both be performed, as is recommended for non-inferiority studies [38]
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