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Specifically, ANO6 upregulates ChaC1, associated with ferroptosis, by increasing intracellular iron and ROS levels, promoting lipid peroxidation and cell death

The administration of GSPs not only improved nerve conduction velocity but also reduced markers of OS in diabetic models ( 4.5 Protection of mitochondrial function Mitochondria are critical for energy production and are also a major source of ROS

97,98 Parks team demonstrated that saponin extract exposure dramatically decreased miR-21-5p expression in HESCs and upregulated caspase-3 expression, which in turn promoted cell apoptosis

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Journal international de vitaminologie et de nutrition