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They do this in several ways: They boost insulin release when blood sugar rises They reduce glucagon (a hormone that increases blood sugar) They slow down stomach emptying, which prevents blood sugar spikes after meals For people with type 2 diabetes, these effects can mean better control of blood sugar levels and lower A1C (a measure of average blood sugar over time)

Being overweight was viewed as evidence of poor choices or insufficient willpower

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DTI), [2] and drug screening assays, such as stem cell-derived hepatocyte-like cells, that are capable of detecting toxicity early in the drug development process

J Pharm Biomed Anal 14:16391644