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doi: 10.3389/fpls.2022.891674 12 DuanY.WangX.JiaoY.LiuY.LiY.SongY.et al

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Furthermore, the binding of plasma-derived molecules to the glycocalyx can result in a local concentration gradient, which is a common feature of the transcriptional and developmental processes that are regulated by growth factors (30, 31)

10 Postnatal environmental factors, including poor diet, exposure to endocrine-disrupting chemicals such as bisphenol A and advanced glycation end products, emerging pollutants (eg, pharmaceuticals, personal care products, microplastics, and nanoparticles), and sedentary lifestyle may further modify these epigenetic changes