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A primary mechanism is its profound influence on gene expression
Multiple mtDNA deletions and copy-number variations are also implicated in PD
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In addition, we observed significantly increased POMC levels and suppressed NpY and AgRP levels in the hypothalamus of VSL#3-treated mice
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Tonazzi, A., Giangregorio, N., Console, L., Palmieri, F., and Indiveri, C., The mitochondrial carnitine acyl-carnitine carrier (SLC25A20): Molecular mechanisms of transport, role in redox sensing and interaction with drugs, Biomolecules , 2021, vol
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