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Surprisingly, addition of GSH to WT cells resulted in an accelerated roGFP2 re-oxidation in the periplasm, whereas GSSG supplementation had no discernible influence (Fig

Kopelman P, Groot Gde H, Rissanen A, Rossner S, Toubro S, Palmer R, et al

This direct delivery allows for rapid absorption of nutrients, which helps combat fatigue, recover from illness or dehydration, and improve overall wellness

Regular progress tracking and diet adjustments will be needed

Neuron 13(5):10311037

The real question sitting under this data is whether coverage strategies keep up, because adherence and cost are still all over the place (and 2027 budgets are going to feel it)