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doi: 10.1172/JCI110908

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Oct 5 : Amgen has interpretation issuesof the confirmatory study variety, at least according to an FDA advisory committee that voted against converting the accelerated approval of its oral G12C KRAS inhibitor Lumakras (sotorasib) to full approval in non-small cell lung cancer (NSCLC)

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Diagnosis should include serum B12 levels interpreted in clinical context, full blood count, and where appropriate, intrinsic factor antibodies and parietal cell antibodies