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The biologically active form of glutathione (GSH)

#GLP-1 receptor agonist exposure with discontinuation before or during early #pregnancy was associated with greater gestational weight gain and increased risk of preterm delivery, gestational #diabetes, and hypertensive disorders in a cohort mainly composed of women with #obesity

The funders had no role in study design, data collection and analysis, decision to publish or preparation of the paper

Within the cyst(e)ine/GSH/GPX4 axis, cysteine is the rate-limiting metabolite for GSH biosynthesis, hence the ferroptosis-inducing activity of cyst(e)ine depletion has largely been attributed to the lowering of intracellular GSH levels and subsequent decrease of GPX4 activity

Injection Site Reactions Mild redness or discomfort at injection site

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