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Limitations Despite the promising analgesic potential of GLP-1RAs, several challenges remain before their widespread application

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This translated into the strong recommendation of the European Society of Cardiology on the use of GLP-1 RAs in patients with T2DM and atherosclerotic cardiovascular disease (ASCVD) in 2019 [73]

36 Alterations of immune mediators in the central and periphery In the brains of ASD patients, the numbers and activation of reactive microglia and astrocytes are increased in multiple brain regions

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