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Highlights : Flavoring chemicals added in electronic cigarettes or e-cigarettes are harmful and cause damage to heart and blood vessels and are not a safe option Previous studies have suggested that e-cigarettes are less likely to cause lung cancer since they contain much lower levels of cancer-causing chemicals, but the effect of e-cigarettes on the heart and blood vessels were not known Use of e-cigarettes particularly among young people has risen alarmingly in the US and the FDA estimates that over 3.5 million middle and high school students experimented using e-cigarettes in 2018 Journal of the American College of Cardiology Using Lab Generated Endothelial Cells To Study Effects of E-Cigarettes Although e-cigarettes reduce the risk of lung cancer, their effect on the heart and blood vessels are less clear and the study aimed to look at the effects of nicotine and flavoring liquids in e-cigarettes on the heart

Caffeine at moderate doses (under 100mg/day for ages 12 to 18 per AAP guidelines) is considered safe for adolescents