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Needing larger quantities of the tobacco product to achieve the same effect

The health risks associated with cigarette smoking are significant

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e-Cigarettes can reduce smokers exposure to carcinogens and other toxic substances found in tobacco, and are very likely less harmful than tobacco cigarettes [71]

Richard Besser, president of the Robert Wood Johnson Foundation and former acting director of the Centers for Disease Control and Prevention, wrote in a statement

These individuals tend to compulsively use nicotine when exposed to nicotine-related cues