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Recruitment of the participants The recruitment of the participants in the RCT took place between June and November 2018

Acetoin and 2,3-pentanedione were detected in 46 and 23 and of the flavors, respectively

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The big three remain ZYN, VELO and Nordic Spirit for mainstream reach, while brands like Killa, Pablo, and BAGZ have carved out loyal followings among more experienced users