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Low dose leptin administration reverses effects of sustained weight-reduction on energy expenditure and circulating concentrations of thyroid hormones

Rizzi C, Tiberi A, Giustizieri M, Marrone MC, Gobbo F, Carucci NM, et al

Expression of mutant SOD1 in neurones did not result in ALS symptoms

Further, this data suggests that rather than buffering oxidative stress to prevent liver damage, GSH synthesis is crucial for maintaining low NRF2 levels and sustaining lipid production by the liver