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The evidence suggests an association and plausible biological mechanisms, but more research is needed to fully characterise this relationship

Understanding when to seek medical advice can facilitate early detection and intervention before significant liver damage occurs

Whilst the cardiovascular and oral cancer risks of chewing tobacco are well-established, the relationship between smokeless tobacco use and fatty liver disease represents an emerging area of research

Nicotine and tobacco constituents may promote hepatic steatosis by increasing insulin resistance and impairing liver fat metabolism

2022:chap 65

But the rate of pancreatic cancer among people using snus was higher than in the control group of non-tobacco product users