doi: 10.32113/wcrj_202011_1752
While GHK-Cu is not a drug or FDA-approved treatment for hair loss, it is included in some over-the-counter formulations for skin rejuvenation and scalp care
Cancer Metastasis Rev 44(1):36 Nabakhteh S et al (2025) Nutritional interventions in amyotrophic lateral sclerosis: from ketogenic diet and neuroprotective nutrients to the microbiota-gut-brain axis regulation
Based on the impact of PfK13 mutations on hemoglobin uptake and GSH levels in the parasite, one can hypothesise that a decrease in redox-active ferrous heme in artemisinin resistant parasites leads to elevated GSH within the cell, potentially making them more tolerant to artemisinin-induced oxidative stress
Lactate is a pro-inflammatory mediator which encourages interleukin-23 (IL-23) transcription in Toll-like receptor (TLR)-stimulated monocytes and macrophages, thereby sustaining IL-23-dependent interleukin-17 (IL-17) secretion and polarizing the immune response against T H 17 cells
Additionally, in a mouse model of ischemic stroke, administration of the prebiotic Puerariae Lobatae Radix-resistant starch (PLR-RS) improved neurological outcomes by restoring gut microbiota balance, enhancing gut barrier function, and increasing melatonin production
