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There is no need to pinch the skin excessively in most patients, though individuals with minimal subcutaneous fat may benefit from a gentle skin fold to ensure subcutaneous rather than intramuscular injection

10.1002/1097-0215(20001101)88:3 3.0.CO;2-F Int

Akhter F, Hashim A, Khan MS, Ahmad S, Iqbal D, Srivastava AK, Siddiqui MH

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The safety of subcutaneous and oral semaglutide will be covered in a separate article in this issue ( Design of The Sustain and Pioneer Programs Both formulations of semaglutide were investigated in comprehensive international clinical development programs