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At 24 h, the upregulation of HMOX1 and GADD45B remained significant in both cell types, but DNAJB1 regulation declined and was no longer significant in HepG2 ATP7B-KO cells

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Basic amino acids confer a positive net charge [155]

however, recent evidence shows that it can also act as a chemopreventive agent

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Kumar A, Vaiphei KK, Singh N, Datta Chigurupati SP, Paliwal SR, Paliwal R et al (2024) Nanomedicine for colon-targeted drug delivery, strategies focusing on inflammatory bowel disease and colon cancer