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Diabetes Care 39 , 17021710 (2016)

Ongoing research may clarify whether certain groups benefit more than others in cognitive outcomes

Risk factors that predispose to development of the condition include female sex (preferentially metabolise acetaminophen to sulfated derivatives) malnutrition, sepsis, diabetes, underlying liver disease and pregnancy

Notably, clinical observations indicate that endocrine therapy resistance is closely associated with oestrogen-dependent redox signal dysregulation mediated by ROS, suggesting that targeting ROS homeostasis may represent a novel breakthrough for reversing drug resistance [127]

Though there were clinical studies consistent with our results [36], it has long been suggested that gradual weight loss is more beneficial for weight regain after treatment discontinuation [37]