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Older adults also show inflammatory markers like IL-6 are often much higher than in young adults, and chronically elevated inflammation is associated with heart disease, diabetes, and cognitive decline

Research progress on berberine with a special focus on its oral bioavailability

In the pathogenesis of OA, the inflammatory response is primarily mediated by the innate immune system [12]

These pathologies are mediated by microbial metabolites, such as SCFAs, microbial endotoxins, and others, that neurologically act on human brain health directly and indirectly

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