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In cells treated with tert -butyl hydroperoxide (TBHP), which induces LPO throughout the cell, NBD-Pen was widely distributed intracellularly, ruling out the possibility that the NBD-Pen puncta depend on the probes biased distribution (Supplementary Fig

Josh Bloom expertly explained, Tylenol "has a low therapeutic index, which means that the difference between an effective dose and a toxic dose is small." Indeed, it is relatively easy to accidentally overdose on acetaminophen

Oxidative stress occurs when the body has too many unstable molecules called pro-oxidants free radicals and reactive oxygen species (ROS)