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Meanwhile, semaglutide 2.4 mg daily (Wegovy, Novo Nordisk) resulted in weight loss of up to 13.9% (95% CI, 11%-16.7%) after 68 weeks of therapy, whereas liraglutide at 3 mg daily (Saxenda, Novo Nordisk) reduced weight by up to 5.8% (95% CI, 3.6%-8%) after 26 weeks

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Intrathecal delivery of an adeno-associated viral vector serotype 9 (AAV9)-human SURF1 (hSURF1) has effectively corrected biochemical abnormalities in mouse models of SURF1 deficiency (107)

Obesity is a common and complex health condition characterized by excessive body fat accumulation

Feldman H, Sepesi B, Leung CH, Lin H, Weissferdt A, Pataer A, William WN Jr, Walsh GL, Rice DC, Roth JA, Mehran RJ, Hofstetter WL, Antonoff MB, Rajaram R, Gibbons DL, Lee JJ, Heymach JV, Vaporciyan AA, Swisher SG , Cascone T