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An important consideration with respect to the ability of GSHee to prevent the deleterious effects of fentanyl on breathing was that the opioid appeared to elicit its full sedative effects in the presence of the GSHee (e.g., righting-reflex times and general observations of behavior could not discriminate between the effects of fentanyl in vehicle-treated or GSHee-treated rats)
Badran, M., Abuyassin, B., Golbidi, S., Ayas, N., & Laher, I
At a fixed supersaturation, a shift in value from 0.05 to 0.1 can lower the critical dry diameter by 20%, meaning that a higher number of particles can be activated as CCN in the context of cloud microphysics 43