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Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial

And because e-cigs are cheaper than cigarettes and perceived to be safe, the fact is, more young non-smokers are becoming smokers

Such risks could be lessened over time as more research on low-nicotine tobacco is conducted

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