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ROS damage to oocytes, sperm, and embryos, and prevention by antioxidants Oocytes Aberrations in microtubule integrity, abundance, and alignment at the metaphase plate have been shown to increase susceptibility to errors in meiotic chromosome segregation in animal oocytes, and may do so in human oocytes, and embryos ( 59 64 )

This review summarizes completed and ongoing clinical trials of triple agonists, with a focus on retatrutidethe most advanced candidate to date

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