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TABLE 3 Role of non-CYP450 proteins involved in drug metabolism/transport and impact of cigarette smoking on their activity

Cigarette smoking can negatively affect male fertility by reducing sperm count, sperm motility, sperm morphology, and sperm DNA quality

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The risk of mouth cancer risk is lower in people with the highest intake of the following foods: Drinking alcohol to excess is another major risk factor of mouth cancer, associated with around a third of cases diagnosed

More details regarding the PRMR process may be found in the PQM Guidebook of Policies and Procedures for Pre-Rulemaking Measure Review and Measure Set Review