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van Empel VP, Lee J, Williams TJ, Kaye DM

PM has been shown to accumulate within the mitochondrion 212 and can disrupt mitochondrial membrane potential 214 , damage mitochondrial structure 212 , alter the mtDNA (strand breaks and methylation) 214,215217 , and activate the mitochondrial programmed apoptosis in pulmonary tissues

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Cliff Johnson, director of the University of Mississippi School of Laws MacArthur Justice Center, said hes heard no talk of challenging the change

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Unlike in many countries where smoking is increasingly seen as socially undesirable, in Indonesia it remains intertwined with masculinity, social etiquette and hospitality, making the epidemic as much a cultural challenge as a public health one