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Key Points Thyroid hormones regulate hepatic lipid metabolism in a cell autonomous manner Thyroid hormone receptors (THR and THR) differentially regulate hepatic lipid metabolism Thyroid hormone induces the expression of genes that encode proteins involved in hepatic lipogenesis Thyroid hormone couples autophagy to mitochondrial fat oxidation to induce ketogenesis Thyroid hormone induces reverse cholesterol transport Thyroid hormone analogues and/or mimetics offer therapeutic alternatives for treatment of lipid-associated hepatic pathologies Abstract It has been known for a long time that thyroid hormones have prominent effects on hepatic fatty acid and cholesterol synthesis and metabolism

The exposure to diesel exhausts increases the formation of DNA adducts in Nrf2 -null mice ( Nrf2 -null mice are more susceptible to cigarette smoke-induced emphysema (Rangasamy et al., 2004), bleomycin-induced pulmonary fibrosis (Cho et al., 2004), and hyperoxic lung injury (Cho et al., 2002b)

Short-term and long-term survival of new neurons in the rat dentate gyrus

A GSH standard is provided to generate a standard curve for the assay and all samples are read off a user generated standard curve

This higher activity results from the insensitivity of ETC to FCCP treatment and is consistent with the limited reserve capacity of Gclc -deficient FoB (Fig

An updated meta-analysis: Risk conferred by glutathione S-transferases (GSTM1 and GSTT1) polymorphisms to age-related cataract